研究目的
To propose and investigate a nanostructure Ag/MoS2/graphene as an optical biosensor with high performance and sensitivity, specifically enhancing sensitivity through the determination of MoS2 layer numbers and metal layer thickness.
研究成果
The proposed SPR optical biosensor with Ag/MoS2/graphene hybrid structure achieves a high sensitivity of 190°/RIU. Optimal performance is obtained with a silver layer thickness of 60 nm, two layers of MoS2, two layers of graphene, and an SF10 prism as the light coupler. The presence of MoS2 layers enhances sensitivity and protects the silver from oxidation, while graphene serves as an effective biological diagnosis component. This design outperforms other recent biosensors in terms of sensitivity and quality factor.
研究不足
The study is based on numerical simulations and theoretical modeling; no experimental validation is provided. Limitations include the assumption of specific refractive indices and layer properties, which may not account for real-world variations or fabrication challenges. The sensitivity is optimized for specific conditions (e.g., wavelength 680 nm, Ag thickness 60 nm), which may limit generalizability.
1：Experimental Design and Method Selection:
The study uses a Kretschmann configuration for the SPR optical biosensor. Mathematical modeling is performed using the Transfer Matrix Method (TMM) for N-layer structures to calculate reflectivity. The Drude model is applied to determine the refractive index of metal layers.
2：Sample Selection and Data Sources:
The sensor layers include a prism (SF10), silver metal layer, MoS2 layers, graphene layers, and a sensing medium with refractive index variations. Parameters are based on literature values and simulations.
3：List of Experimental Equipment and Materials:
Materials include SF10 prism, silver (Ag), molybdenum disulfide (MoS2), graphene, and sensing medium. No specific equipment brands or models are mentioned; the study is theoretical and numerical.
4：Experimental Procedures and Operational Workflow:
The design involves depositing layers (prism, Ag, MoS2, graphene) and analyzing sensitivity, detection accuracy, and quality factor through numerical simulations at a wavelength of 680 nm. Variations in layer thickness and numbers are investigated.
5：Data Analysis Methods:
Sensitivity is calculated as the ratio of SPR angle shift to refractive index change. Detection accuracy and quality factor are derived from SPR curve characteristics. Results are plotted and tabulated for comparison.
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