摘要： This study evaluates the performance of the Siemens Biograph Vision digital PET/CT system (Siemens Healthineers, Knoxville, USA) according to the NEMA NU 2‐2012 standard (published by the National Electrical Manufacturers Association (NEMA)) to allow for a reliable, reproducible, and inter‐system comparable performance measurement. Methods: The new digital PET/CT features silicon photomultiplier (SiPM)‐based detectors with 3.2 mm lutetium oxyorthosilicate (LSO) crystals and full coverage of the scintillator area. The PET components incorporate eight rings of 38 detector blocks and each block contains 4x2 mini‐blocks. Each mini‐block consists of a 5x5 LSO‐array of 3.2x3.2x20 mm crystals coupled to a SiPM‐array of 16x16 mm, resulting in an axial field of view (FOV) of 26.1 cm. In this study PET/CT system performance will be evaluated conform the NEMA NU 2‐2012 standard with additional measurements described in the new NEMA NU 2‐2018 standard. Spatial resolution, sensitivity, count‐rate performance, accuracy of attenuation and scatter correction, Time‐of‐Flight (TOF) performance, and image quality will be determined. Measurements will be directly compared to results from its predecessor, the Biograph mCT Flow, using existing literature. Moreover, feasibility to comply with the European Association of Nuclear Medicine (EANM) Research Ltd (EARL) criteria will be evaluated and some illustrative patient PET images will be shown. Results: The Biograph Vision shows a transverse (resp. axial) spatial resolution at Full Width Half Maximum (FWHM) of 3.6 mm (resp. 3.5 mm) at 1 cm offset of the center of the FOV (measured with a 22Na 0.25 mm point‐source), a NEMA sensitivity of 16.4 kcps/MBq, and a NEMA peak NECR of 306 kcps at 32 kBq/mL. TOF resolution varied from 210 to 215 as count‐rate increased up to the peak NECR. The overall image contrast seen with the NEMA image quality phantom ranged from 77.2% to 89.8%. Furthermore, the system was able to comply with the current and future EARL performance criteria. Conclusions: The Biograph Vision outperforms the analog Biograph mCT Flow and the system is able to meet European harmonizing performance standards.