研究目的
To present an oval-shaped sensor design for measuring glucose concentration in aqueous solution, inspired by metamaterial properties, for potential non-invasive blood glucose analysis.
研究成果
The oval-shaped metamaterial sensor demonstrates potential for glucose sensing with a sensitivity of 0.037 GHz/(30 mg/dL). It exhibits double negative (DNG) properties and minimal absorption, making it suitable for biosensing applications. Experimental results validate the simulation, indicating feasibility for non-invasive glucose monitoring.
研究不足
The experimental setup had difficulties in precise sample positioning, leading to sudden resonances. The sensor's performance may be affected by fabrication inaccuracies and environmental factors. Further optimization is needed for real-world applications, such as improving sensitivity and miniaturization for wearable devices.
1：Experimental Design and Method Selection:
The sensor design is based on metamaterial properties, using a finite integration technique (FIT) in CST Microwave Studio for simulation. Analytical methods include lumped element modeling and the Direct-Refractive Index (DRI) method for parameter extraction.
2：Sample Selection and Data Sources:
Glucose aqueous solutions with dielectric constants from 55 to 87 were used. Human serum samples with glucose concentrations from 68 to 150 mg/dL were tested experimentally.
3：List of Experimental Equipment and Materials:
Rogers RO4350B substrate, copper patch, Vector Network Analyzer (VNA) Agilent N5227A, injection needle for sample application.
4：Experimental Procedures and Operational Workflow:
The sensor was designed and simulated in CST. Fabricated unit cells were tested with glucose solutions applied to the sensing area, and S-parameters were measured using the VNA.
5：Data Analysis Methods:
S-parameters (S11, S21) were analyzed to determine resonance frequency shifts. Sensitivity was calculated based on permittivity changes.
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