研究目的
To create high-functional ophthalmological hydrophilic lenses with high water content, high wettability, ultraviolet ray blocking, and electromagnetic wave blocking effects by incorporating PEGMEMA, 2,4-dihydroxybenzophenone, and ITO nanoparticles as additives in a stepwise polymerization process.
研究成果
The stepwise addition of PEGMEMA, 2,4-dihydroxybenzophenone, and ITO nanoparticles successfully enhanced the ophthalmological hydrophilic lenses with high water content, wettability, UV blocking, and electromagnetic wave shielding capabilities, making them suitable for use with electronic devices like smartphones.
研究不足
The study may have limitations in scalability for industrial production, potential biocompatibility issues not fully addressed, and the specific electromagnetic wave frequencies tested are not detailed, which could affect applicability. Optimization of additive ratios for minimal impact on optical properties might be needed.
1:Experimental Design and Method Selection:
A stepwise copolymerization approach was used, involving primary, secondary, and tertiary polymerizations to sequentially add functional additives (PEGMEMA for hydrophilicity, 2,4-dihydroxybenzophenone for UV blocking, and ITO nanoparticles for electromagnetic wave shielding) to a base ophthalmological hydrophilic lens material (HEMA, PVP, EGDMA, AIBN). Thermal polymerization at 100°C via cast molding was employed for all steps.
2:Sample Selection and Data Sources:
Samples were prepared with varying ratios of additives (e.g., PEGMEMA from 1% to 20%, 2,4-dihydroxybenzophenone from
3:1% to 0%, ITO nanoparticles at 05% and 10%) based on the base composition. Physical and optical properties were measured after hydration in 9% physiological saline for over 24 hours. List of Experimental Equipment and Materials:
Materials included HEMA, PVP, EGDMA, AIBN (from JUNSEI), PEGMEMA, 2,4-dihydroxybenzophenone, ITO nanoparticles (from Sigma-Aldrich). Equipment included a microwave oven for drying, XS205 dual-range scale (METTLER TOLEDO) for weight measurement, ABBE refractometer (ATAGO) for refractive index, Cary 60 UV-vis spectroscope (Agilent) with Cary Win UV software for transmittance, XE-100 AFM (Park system), and FESEM (JSM-7500F+EDS, Oxford) for surface analysis.
4:Experimental Procedures and Operational Workflow:
For each polymerization step, mixtures were prepared according to specified percentages, polymerized at 100°C using cast molding, hydrated, and then measured for water content (gravimetric method), refractive index, optical transmittance (UV and visual ranges), contact angle, and surface morphology (AFM and FE-SEM). Five measurements were averaged for each property.
5:Data Analysis Methods:
Data were analyzed using averages of multiple measurements; statistical techniques were not specified, but standard deviations or similar may have been implied for reliability.
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ITO nanoparticles
30 nm
Sigma-Aldrich
Additive for electromagnetic wave shielding
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Cary 60 UV-vis spectroscope
Cary 60
Agilent
Measuring spectral transmittance of samples
Cary 60 UV-Vis Spectrophotometer
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FESEM
JSM-7500F+EDS
Oxford
Surface analysis and nanoparticle presence detection
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HEMA
JUNSEI
Monomer used in polymerization for basic lens material
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AIBN
JUNSEI
Initiator for polymerization
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PVP
Sigma-Aldrich
Cross-bonding material in polymerization
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PEGMEMA
Sigma-Aldrich
Additive to enhance water content and wettability
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EGDMA
Sigma-Aldrich
Cross-bonding material in polymerization
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2,4-dihydroxybenzophenone
Sigma-Aldrich
Additive for UV blocking
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XS205 dual-range scale
XS205
METTLER TOLEDO
Measuring weights of dry and hydrated samples
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ABBE refractometer
ATAGO
Measuring refractive index of lens samples
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Cary Win UV software
Agilent
Analyzing transmittance data
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AFM
XE-100
Park system
Surface analysis of lens samples
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