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Effects of Substrate Preheating Temperatures on the Microstructure, Properties, and Residual Stress of 12CrNi2 Prepared by Laser Cladding Deposition Technique
摘要： The 12CrNi2 alloy steel powder studied in the present paper is mainly used to manufacture camshafts for nuclear power emergency diesel engines. Laser cladding deposition is of great signi?cance for the manufacture of nuclear power emergency diesel camshafts, which has the advantages of reducing material cost and shortening the manufacturing cycle. However, due to the extremely uneven heating of the components during the deposition process, a complex residual stress ?eld occurs, resulting in crack defects and residual deformation of the components. In the present paper, 12CrNi2 bulk specimens were prepared on the Q460E high-strength structural steel substrate at different preheating temperatures by laser cladding deposition technique, and a ?nite element residual stress analysis model was established to investigate the effects of different preheating temperatures on the microstructure, properties, and residual stress of the specimens. The results of the experiments and ?nite element simulations show that with the increase of preheating temperature, the content of martensite/bainite in the deposited layer decreases, and the ferrite content increases. The proper preheating temperature (150 ?C) has good mechanical properties. The residual stress on the surface of each specimen decreases with the increase of the preheating temperature. The longitudinal stress is greater at the rear-end deposition part, and the lateral residual stress is greater on both sides along the scanning direction.
关键词： substrate preheating,12CrNi2 alloy steel powder,residual stress,laser cladding deposition,microstructure and properties
更新于2025-11-28 14:24:20
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Numerical and experimental investigation on microstructure and residual stress of multi-pass hybrid laser-arc welded 316L steel
摘要： In multi-layer welding, the interaction between the weld beads had a great impact on the performance of the overall joint. Therefore, experimental research and thermal-plastic analysis of 316L stainless steel multi-layer hybrid laser-arc welding were performed. The reasonable heat sources were proposed to simulate hybrid laser-arc welding (HLAW) and laser beam welding (LBW). The simulation results of temperature field and residual stress distribution were both validated and in accordance with experimental measurements. On this basis, Combining the simulated results with the metallurgical analysis, the microstructure of multi-layer weld was divided according to temperature histories. The formation mechanism of feathery ferrite precipitated in the re-melting zone (RZ) was analyzed. The feathery ferrite could increase the micro-hardness of the interlaminar position of weld. Moreover, the residual stress along the multi-layer weld thickness direction was simulated and X-ray diffraction (XRD) measured, which indirectly demonstrated the size and orientation variation of the grains in the RZ.
关键词： Residual stress,Microstructure,FE analysis,Hybrid laser-arc welding
更新于2025-11-28 14:24:20
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Effects of phase transition temperature and preheating on residual stress in multi-pass & multi-layer laser metal deposition
摘要： To investigate the influences of phase transition temperature and preheating on the residual stress of multi-layer and multi-pass laser metal deposition (LMD), the multi-layer and multi-pass LMD, with and without preheating, were performed using five kinds of alloy with different phase transition features, and their residual stresses were measured using the hole drilling method. A finite-element (FE) model incorporating the phase transition was developed based on experimentally obtained physical property data. The results demonstrated that the low-temperature solid phase transition has a tensile stress relaxation effect, which leads to the formation of a compressive stress area. This relaxation effect was observed to decrease with the increase of the phase transition temperature. The high-temperature solid phase transition has no significant tensile stress relaxation effect during the multi-layer and multi-pass LMD process, which is different from the single track LMD. when the solid phase transition temperature is low, the preheating can improve the uniformity of the stress field only to a certain extent. However, when the preheating increases the lowest temperature of the thermal cycle and makes it higher than the starting point temperature of the solid phase transition, the tensile stress relaxation effect of the solid phase transition can be brought into full play.
关键词： Finite element analysis,Preheating,phase transition temperature,Residual stress,Laser metal deposition
更新于2025-11-28 14:24:20
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Optimization of Residual Stresses in Laser-Mixed WC(Co, Ni) Coatings
摘要： A ternary mixture of tungsten carbide (WC), cobalt (Co), and nickel (Ni) powders is prepared to form ceramic-metal composite coatings employed for laser cladding of 40Cr steel. This coating is investigated using the mixture design to evaluate the influence of its ratios on the residual stresses in the clads. The WC/Co/Ni ternary mixture exhibits higher residual stresses than those of the Co/Ni or WC/Ni binary mixtures, except for the WC/Co one. Single WC, Co, or Ni designs illustrate a high sensitivity of residual stresses, cracks pass through the interior of WC particles rather than around them, and the cracks mostly propagate along the eutectic phases at 50%Co–50%WC. A reduced special quartic model in the mixture design exhibits excellent fit, predicted and experimental values of residual stresses for these laser clads are in good agreement.
关键词： residual stress optimization,mixture,reduced special quartic model,tungsten carbide
更新于2025-11-28 14:24:20
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Formation of ordered defect structures in lithium niobate crystals of different chemical composition at non-equilibrium processes of different nature
摘要： Ordered defective structures in lithium niobate crystals have been established. The phenomenon is a result of non-equilibrium processes of a different nature: photo-induced light scattering, laser ablation, and creation of cracks during relieving mechanical stresses. The shape of such structures depends on the nature and energy that affect a crystal. A number of concentric areas with a different density of laser-induced defects with a changed refractive index appear during photoinduced light scattering. Concentric clusters of microdomains appear in a macrodomain of another sign at laser ablation as a result of local switching under impulse laser radiation. A number of microcracks with a fractal structure appear near main macro-crack during cracking under mechanical stress. Thus, appearance of ordered defective structure occurs not only in the local spot of direct exposure to laser radiation, mechanical stress, etc., but also in some volume of a crystal around it.
关键词： Doping,Laser ablation,Lithium niobate,Mechanical stress,Defective structure,Photorefractive effect
更新于2025-11-21 11:24:58
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Effect of thermal stress induced by femtosecond laser on fracture toughness of fine-grained alumina
摘要： The ultra-sharp V-notch with tip radius smaller than 0.5 μm was cut by femtosecond laser on the fine-grained alumina ceramic bars to measure the fracture toughness by single-edge V-notched beam (SEVNB) method. In order to relieve the effect of thermal stresses induced by laser on fracture toughness testing, the samples with V-notch were annealed before measurement. The morphologies of the notch tip were analyzed by SEM and micro-Raman spectra. Results reveal that the fracture toughness value of this fine-grained alumina with thermal stresses on the V-notch is equal to that after annealing, and the effect of thermal stresses induced by laser on the fracture toughness can be ignored.
关键词： SEVNB,Fracture toughness,Laser processing,Thermal stress,Alumina
更新于2025-11-21 11:18:25
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The molecular chaperone sigma 1 receptor mediates rescue of retinal cone photoreceptor cells via modulation of NRF2
摘要： Sigma 1 receptor (Sig1R), a putative molecular chaperone, has emerged as a novel therapeutic target for retinal degenerative disease. Earlier studies showed that activation of Sig1R via the high-affinity ligand (+)-pentazocine ((+)-PTZ) induced profound rescue of cone photoreceptor cells in the rd10 mouse model of retinitis pigmentosa; however the mechanism of rescue is unknown. Improved cone function in (+)-PTZ-treated mice was accompanied by reduced oxidative stress and normalization of levels of NRF2, a transcription factor that activates antioxidant response elements (AREs) of hundreds of cytoprotective genes. Here, we tested the hypothesis that modulation of NRF2 is central to Sig1R-mediated cone rescue. Activation of Sig1R in 661W cone cells using (+)-PTZ induced dose-dependent increases in NRF2-ARE binding activity and NRF2 gene/protein expression, whereas silencing Sig1R significantly decreased NRF2 protein levels and increased oxidative stress, although (+)-PTZ did not disrupt NRF2-KEAP1 binding. In vivo studies were conducted to investigate whether, in the absence of NRF2, activation of Sig1R rescues cones. (+)-PTZ was administered systemically for several weeks to rd10/nrf2+/+ and rd10/nrf2-/- mice. Through post-natal day 42, cone function was significant in rd10/nrf2+/+, but minimal in rd10/nrf2-/- mice as indicated by electroretinographic recordings using natural noise stimuli, optical coherence tomography and retinal histological analyses. Immunodetection of cones was limited in (+)-PTZ-treated rd10/nrf2-/-, though considerable in (+)-PTZ-treated rd10/nrf2+/+mice. The data suggest that Sig1R-mediated cone rescue requires NRF2 and provide evidence for a previously-unrecognized relationship between these proteins.
关键词： retinitis pigmentosa,NRF2-KEAP1,retinal neuroprotection,retina,rd10 mouse,NRF2-Neh luciferase assay,oxidative stress
更新于2025-11-21 11:08:12
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Simvastatin Protects Photoreceptors from all-trans-retinal Induced Oxidative Stress with Up-regulation of Interphotoreceptor Retinoid Binding Protein
摘要： Background and Purpose Simvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor with multiple targets and effects. It protects neurons in the brain but its protective effects on photoreceptors are unclear. In this study, we evaluated the neuroprotective effect of simvastatin on photoreceptors exposed to stress induced by all-trans-retinal (atRAL). Experimental approach AlamarBlue and lactate dehydrogenase assays were used to evaluate the viability and metabolic activity of Y79 cells (a retinoblastoma cell line) exposed to atRAL-induced stress with or without simvastatin pre-treatment. Changes in cellular reactive oxygen species were evaluated using flow cytometry and mitochondrial stress markers JC-1 and HSP60. Changes in levels of the photoreceptor-specific markers cone-rod homeobox protein (CRX) and Interphotoreceptor Retinoid Binding Protein (IRBP) were evaluated with Western blotting. The results were validated in ex vivo human retinal explants and a mouse model of photoreceptor degeneration. Key results Simvastatin improved mitochondrial function, alleviated oxidative stress and upregulated the photoreceptor specific markers IRBP and its upstream regulator CRX in Y79 cells and ex vivo human retinal explants under atRAL-induced stress. Simvastatin attenuated photoreceptor degeneration in association with upregulation of IRBP and CRX expression after knockdown of IRBP in a murine model. Conclusion and implications Our findings suggest that simvastatin has a novel role in protecting photoreceptors from atRAL-induced stress. Simvastatin treatment resulted in upregulation of IRBP and its upstream transcription factor CRX in Y79 cells, ex vivo human retinal explants and murine retinas in vivo. Further studies of simvastatin to treat photoreceptor degeneration are warranted.
关键词： photoreceptors,IRBP,CRX,oxidative stress,all-trans-retinal,Simvastatin
更新于2025-11-21 11:08:12
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Chemically exfoliated 1T-phase transition metal dichalcogenide nanosheets for transparent antibacterial applications
摘要： Two-dimensional transition metal dichalcogenides (TMDs) are promising materials for a range of applications owing to their intriguing properties including the excellent electrical performance and biocompatibility. Strikingly, 1T-phase TMDs have attracted significant interest based on their metallic properties with octahedral metal coordination where the phase transition can occur from the semiconducting 2H-phase to metallic 1T-phase by chemical intercalation-induced exfoliation process. In this regard, 1T-phase TMDs have great potential in antibacterial agents in terms of effective charge transfer between the bacterial membrane and TMD nanosheets while their biological interactions have been underexplored. To bridge this gap, we herein investigate the antibacterial activities of various 1T-phase TMDs including molybdenum disulfide (MoS2), tungsten disulfide (WS2), and molybdenum diselenide (MoSe2) toward Gram-negative bacteria Escherichia coli that exhibit the reduction of bacterial viability caused by the production of reactive oxygen species, oxidation of glutathione and other chemical functionalities. The effective antibacterial capacity of metallic 1T-phase TMDs is observed and their bactericidal mechanisms are investigated in terms of their electrical conductivity and chemical oxidation property that induce the charge transfer from bacterial membrane to TMDs leading to the continuous disruption of bacteria and loss of cellular components. Furthermore, we demonstrated the transparent antibacterial films consisting of 1T-phase TMDs in which TMD nanosheets are immobilized on the surfaces and their basal planes play an important role in antibacterial actions for practical biomedical applications. Thus, our findings provide new insights into the great potential of 1T-phase TMDs as promising building blocks for antibacterial surfaces and contribute to the widespread use of 1T-phase TMDs for practical biomedical applications.
关键词： 1T-phase,charge transfer,antibacterial activity,oxidative stress,transition metal dichalcogenide
更新于2025-11-21 11:08:12
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[Lecture Notes in Mechanical Engineering] Advances in Thin Films, Nanostructured Materials, and Coatings (Selected Papers from the 2018 International Conference on “Nanomaterials: Applications & Properties”) || Stain Effect on the Properties of Polar Dielectric Thin Films
摘要： Low cost scalable processing and substrates are critical for optimized polar dielectric performance of functional oxide thin ?lms if they are to achieve commercialization. Here, we present a comprehensive investigation of the role low-cost MgO, Al2O3, SrTiO3 and Si substrates on the structural and electrical properties of sol-gel derived SrTiO3 (ST) and K0.5Na0.5NbO3 (KNN) thin ?lms. The substrate is found to have a strong effect on the stress/stain state and, consequently, on the dielectric and ferroelectric response of the ?lms. A tensile stress induced in-plane by the thermal expansion mismatch between the substrates and the ?lms observed for ST and KNN ?lms deposited on platinized Al2O3 and Si substrates, respectively, lowers the relative permittivity and remanent polarization values in the parallel plate capacitor geometry. In contrast, a compressive stress/strain observed for ST ?lms deposited on MgO/Pt and KNN ?lms on SrTiO3/Pt substrates result in superior polarization and dielectric permittivity, corresponding to enhanced out-of-plane displacement of Ti4+ ions in ST ?lms and Nb5+ ions in KNN ?lms. It is thus demonstrated that for polycrystalline polar dielectric thin ?lms the relative permittivity and polarization may be optimized through an induced compressive stress state.
关键词： Dielectric properties,Sol-gel,Thin ?lms,Stress/strain,Thermal expansion,Ferroelectric hysteresis
更新于2025-11-14 17:28:48