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Integration of spectroscopy and imaging to optimize evaluation of voiding dysfunction
摘要： Voiding dysfunction occurs due to the interplay of anatomic, physiologic and functional elements. Hence, integration of new imaging and spectroscopy modalities offers the potential for improving patient assessment by enabling the causal structural defects, formal staging of pelvic floor dysfunction and underlying physiologic mechanisms to be better defined. The purpose of this review is to outline the limitations of current imaging, and highlight the advantages of newer technologies in the evaluation of patients with voiding dysfunction due to loss of structural integrity of the pelvic floor.
关键词： fMRI,pelvis,MRI,prolapse,voiding dysfunction,fNIRS,NIRS,MRO
更新于2025-09-19 17:15:36
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[IEEE 2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) - Bangkok, Thailand (2019.4.11-2019.4.14)] 2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) - Free-spaced-coupled Liquid Crystalline Broadband Optoacoustic Sensors
摘要： Near-infrared spectroscopy (NIRS) has been proposed as a suitable technique for the analysis of cerebral autoregulation as it provides a simpler acquisition methodology and more artifact-free signal. A number of sophisticated wavelet transform methods have recently emerged to quantify the cerebral autoregulation mechanism using NIRS and blood pressure signals. These provide an enhanced partitioning of signal information via the time–frequency plane, which facilitates improved extraction of the components of interest. This area is reviewed, and enhancements to this form of analysis are suggested.
关键词： NIRS,Cerebral autoregulation,wavelet transform
更新于2025-09-19 17:13:59
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[IEEE 2019 Photonics North (PN) - Quebec City, QC, Canada (2019.5.21-2019.5.23)] 2019 Photonics North (PN) - Femtosecond-Laser-Induced Blister Formation on Polymer Thin Films
摘要： Near-infrared spectroscopy (NIRS) has been proposed as a suitable technique for the analysis of cerebral autoregulation as it provides a simpler acquisition methodology and more artifact-free signal. A number of sophisticated wavelet transform methods have recently emerged to quantify the cerebral autoregulation mechanism using NIRS and blood pressure signals. These provide an enhanced partitioning of signal information via the time–frequency plane, which facilitates improved extraction of the components of interest. This area is reviewed, and enhancements to this form of analysis are suggested.
关键词： NIRS,Cerebral autoregulation,wavelet transform
更新于2025-09-19 17:13:59
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Wearable SiPM-based NIRS Interface Integrated with Pulsed Laser Source
摘要： We present the design of a miniaturized probe integrating silicon photomultiplier and light-pulsing electronics in a single 2x2mm2 CMOS chip which includes functional blocks such as a fast pulse-laser driver and synchronized single-photon detection circuit. The photon pulses can be either counted on-chip or processed by an external high-speed electronic module such as time-corelated single photon counting (TCSPC) unit. The integrated circuit was assembled on a printed circuit board (PCB) and also on a 2.5D silicon interposer platform of size 1 cm and interfaced with a silicon photomultiplier (SiPM), vertical cavity surface emitting laser (VCSEL) and other ancillary components such as capacitors and resistors. Our approach of integrating an optical interface to optimize light collection on the small active area and light emission from the vertical-cavity surface-emitting laser (VSCEL) will facilitate clinical adoption in many applications and change the landscape of Near Infrared Spectroscopy (NIRS) hardware commercially due to significant optode-size reduction and the elimination of optical fibers.
关键词： Near-Infrared Spectroscopy (NIRS),Time-Domain (TD),complementary metal-oxide-semiconductor (CMOS),Vertical Cavity Surface Emitting Laser (VCSEL),Silicon Photomultiplier (SiPM),Optical Probe
更新于2025-09-11 14:15:04
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Revolutionizing Tropical Medicine (Point-of-Care Tests, New Imaging Technologies and Digital Health) || The Use of Near-Infrared Spectroscopy to Monitor Tissue Oxygenation, Metabolism and Injury in Low Resource Settings
摘要： In a low resource setting there are many barriers for providing the standard of healthcare that is normal in developed countries. Modern healthcare largely depends on reliable and accurate medical devices that can diagnose disease, monitor treatment and provide accurate prognostic information. Often medical devices are associated with high costs for purchasing and maintenance that often includes costs for a large number of consumables. In addition, a particular infrastructure is required and highly trained staff are needed to operate these devices. To be successful and useful in low‐ and middle‐income countries (LMICs), a medical device needs to be inexpensive, portable, safe, non‐invasive, easy to use and interpret, and battery‐powered. Near‐infrared spectroscopy (NIRS) is a medical device that fulfills all of these requirements and thus has great potential to make an impact on healthcare in LMICs. Its most important use to date has been in neurological monitoring. Its success in this field is due to its low cost, ease of use and ability to be used in a low resource environment.
关键词： metabolism,Near‐Infrared Spectroscopy,NIRS,tissue oxygenation,injury,low resource settings
更新于2025-09-11 14:15:04
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NIRS cerebral patterns in healthy late preterm and term infants are gender- and gestational age-dependent
摘要： Near infrared spectroscopy (NIRS) has been proposed to provide reliable information concerning brain oximetry and tissue activation level in the perinatal period. We aimed to investigate whether NIRS brain patterns in healthy preterm and term infants were gender- and gestational age-dependent. Methods: We conducted an observational study in 74 newborns, from consecutive singleton pregnancies, of whom 37 were born at term (male: n=19 female: n=18) and 37 (male: n=18 female: n=19) were preterm. Cerebral oximetry (crSO2) and fractional tissue oxygen extraction (cFTOE), were recorded on the 5th day from birth. Results: crSO2 was significantly higher and cFTOE lower (P<0.001, for both) in the preterm female than male group. At term crSO2 was significantly higher and cFTOE lower (P<0.001, for both) in males. crSO2 (male: R=0.84, P<0.001; female: R=0.74, P= P<0.001) and cFTOE (male: R=0.72, P<0.001; female: R=0.72, P<0.001) in male and female groups correlated positively with gestational age at recording. Conclusion: Different brain oximetry between males and females in preterm and term gestational ages, may suggest that in the perinatal period brain development is gender- and time-dependent. Data support the use of NIRS as a feasible tool for non-invasive cerebral monitoring.
关键词： newborn,NIRS,gender,brain development
更新于2025-09-10 09:29:36
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The association between near-infrared spectroscopy-derived and flow-mediated dilation assessment of vascular responsiveness in the arm
摘要： Introduction: Following a period of blood flow occlusion, the near-infrared spectroscopy (NIRS)-derived reperfusion slope of the oxygen saturation signal (StO2) is a measure of microvascular responsiveness that has been shown to be positively correlated with flow mediated dilation (FMD) assessment of conduit artery function in the lower limb vasculature. Given that previously established differences in structure and function of the vessels in the upper compared to the lower limbs may change this relationship, investigating whether this correlation between the reperfusion slope of the StO2 and the FMD response is maintained in upper limbs is important. Accordingly, this study investigated the correlation between the reperfusion slope of the StO2 and FMD in the arm vasculature. Methods: 18 physically active individuals were submitted to a vascular occlusion test (VOT). Microvascular responsiveness was calculated as the NIRS-derived reperfusion slope assessed in a forearm muscle. Macrovascular responsiveness was assessed at the brachial artery and calculated as a percent of change in FMD (%FMD). Results: A statistically significant correlation (r= 0.66; P = 0.001) was found between the reperfusion slope and %FMD response. Conclusion: The significant correlation between the reperfusion slope in the forearm muscle and %FMD in the brachial artery, reinforces the relationship between downstream and upstream vascular reactivity in healthy human limbs.
关键词： Vascular function.,NIRS,FMD
更新于2025-09-10 09:29:36
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Cetane number prediction of waste cooking oil-derived biodiesel prior to transesterification reaction using near infrared spectroscopy
摘要： Fifty waste cooking oils (WCOs) were transesterified with methanol (1:8 WCO:methanol molar ratio) at 60 °C for 60 min using NaOH as catalyst (1% wt.). Fatty acid methyl ester (FAME) composition of the resulting biodiesels was analysed by gas chromatography, and near infrared (NIR) spectra of these biodiesels and those of the starting WCOs were acquired. Biodiesel cetane number was then calculated from both FAME composition and from biodiesel NIR spectra, this last technique using the former one as reference data. Because of transesterification does not modify fatty acid distribution of the starting WCO, and the similarity between biodiesel and WCO NIR spectra, biodiesel cetane number was successfully predicted from WCO NIR spectra, achieving RPD (ratio of performance to deviation) of 3.83. Therefore, biodiesel cetane number (and, as consequence, any other biodiesel property related to FAME composition) can be predicted by NIR spectroscopy before performing the transesterification reaction, which allows beforehand selecting the most suitable substrates for biodiesel production.
关键词： Waste cooking oil,NIRS,Biodiesel,Cetane number
更新于2025-09-09 09:28:46
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Research on the Frontal lobe Activation Effect of Music Therapy?。璄ffect of Listening Music on Frontal lobe Activation by Using Near-Infrared Spectroscopy－; 音楽療法の脳機能に関する研究 ―近赤外分光法を用いた音楽聴取時の脳活動の評価―;
摘要： This study used topographic near-infrared spectroscopy (NIRS) to characterize frontal lobe activation while individuals actively or passively listened to exciting or calm music. Participants were 22 healthy female volunteers (mean age, 21 ± 4.1 years). Initial analysis showed that activation. Therefore, active music therapy may be more effective than passive music therapy with respect to brain activation. Such active therapy (i.e., playing rather than listening to music) may improve functional and psychological status, and cooperative abilities. oxy-Hb significantly decreased in many channels when subjects listened to calm music. In contrast, oxy-Hb significantly increased when subjects listened to lively music. In addition, after listening to calm music, cortisol, α -amylase, and immunoglobulin A significantly decreased. A subsequent analysis showed that oxy-Hb significantly increased when subjects listened to music while clapping to its rhythm compared with when subjects listened to music only. Our study suggests that calm music reduces levels of human stress and enables effective relaxation. In addition, our data suggests that clapping to the rhythm of music increases brain NIRS, Frontal lobe, exciting music and calm music, Active and passive musical listening, Music therapy
关键词： Active and passive musical listening,Music therapy,NIRS,Frontal lobe,exciting music and calm music
更新于2025-09-04 15:30:14
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Changes in cerebral oxygenation and cerebral blood flow during hemodialysis – A simultaneous near-infrared spectroscopy and positron emission tomography study
摘要： Near-infrared spectroscopy (NIRS) is used to monitor cerebral tissue oxygenation (rSO2) depending on cerebral blood flow (CBF), cerebral blood volume and blood oxygen content. We explored whether NIRS might be a more easy applicable proxy to [15O]H2O positron emission tomography (PET) for detecting CBF changes during hemodialysis. Furthermore, we compared potential determinants of rSO2 and CBF. In 12 patients aged (cid:2) 65 years, NIRS and PET were performed simultaneously: before (T1), early after start (T2), and at the end of hemodialysis (T3). Between T1 and T3, the relative change in frontal rSO2 (DrSO2) was (cid:3)8 (cid:4) 9% (P ? 0.001) and (cid:3)5 (cid:4) 11% (P ? 0.08), whereas the relative change in frontal gray matter CBF (DCBF) was (cid:3)11 (cid:4) 18% (P ? 0.009) and (cid:3)12 (cid:4) 16% (P ? 0.007) for the left and right hemisphere, respectively. DrSO2 and DCBF were weakly correlated for the left (r 0.31, P ? 0.4), and moderately correlated for the right (r 0.69, P ? 0.03) hemisphere. The Bland-Altman plot suggested underestimation of DCBF by NIRS. Divergent associations of pH, pCO2 and arterial oxygen content with rSO2 were found compared to corres- ponding associations with CBF. In conclusion, NIRS could be a proxy to PET to detect intradialytic CBF changes, although NIRS and PET capture different physiological parameters of the brain.
关键词： cerebral oximetry,hemodialysis,water-PET,Brain perfusion,NIRS
更新于2025-09-04 15:30:14