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- 摘要
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- 实验方案
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Oxygen Saturation Measurements from Green and Orange Illuminations of Multi-Wavelength Optoelectronic Patch Sensors
摘要： Photoplethysmography (PPG) based pulse oximetry devices normally use red and infrared illuminations to obtain oxygen saturation (SpO2) readings. In addition, the presence of motion artefacts severely restricts the utility of pulse oximetry physiological measurements. In the current study, a combination of green and orange illuminations from a multi-wavelength optoelectronic patch sensor (mOEPS) was investigated in order to improve robustness to subjects’ movements in the extraction of SpO2 measurement. The experimental protocol with 31 healthy subjects was divided into two sub-protocols, and was designed to determine SpO2 measurement. The datasets for the first sub-protocol were collected from 15 subjects at rest, with the subjects free to move their hands. The datasets for the second sub-protocol with 16 subjects were collected during cycling and walking exercises. The results showed good agreement with SpO2 measurements (r = 0.98) in both sub-protocols. The outcomes promise a robust and cost-effective approach of physiological monitoring with the prospect of providing health monitoring that does not restrict user physical movements.
关键词： green and orange illuminations,optoelectronic patch sensor (mOEPS),oxygen saturation (SpO2),physical movement,pulse oximetry
更新于2025-09-23 15:23:52
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[IEEE 2018 IEEE ANDESCON - Santiago de Cali, Colombia (2018.8.22-2018.8.24)] 2018 IEEE ANDESCON - Development of a Low-Cost Pulse Oximeter Simulator for Educational Purposes
摘要： Medical instrumentation devices are crucial to determine health conditions in humans. Teaching biomedical instrumentation requires a perfect combination of practice and theory. Therefore, the use of physiological signals simulators such as a %SpO2 becomes important as a teaching strategy. The objective of this project is to develop and implement an oxygen saturation simulator, for use in the biomedical instrumentation courses. The development process began by establishing the requirements of the simulator and designing a graphical user interface to control the simulator parameters. Subsequently, a circuit capable of materializing the simulated signals from the interface was developed, together with a probe or artificial finger that was to be introduced inside the objective pulse oximeter. Finally, the systems were integrated into the simulator
关键词： simulation,low cost,Pulse oximetry,biomedical instrumentation,education
更新于2025-09-23 15:23:52
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The Impact of Averaging Window Length on the “Desaturation” Indexes Obtained Via Overnight Pulse Oximetry at High Altitude
摘要： To determine the impact of averaging window-length on the “desaturation” indexes (DIs) obtained via overnight pulse oximetry (SpO2) at high altitude. Overnight SpO2 data were collected during a 10-day sojourn at high altitude. SpO2 was obtained using a commercial wrist-worn finger oximeter whose firmware was modified to store unaveraged beat-to-beat data. Simple moving averages of window lengths spanning 2 to 20 cardiac beats were retrospectively applied to beat-to-beat SpO2 datasets. After SpO2 artifacts were removed, the following DIs were then calculated for each of the averaged datasets: oxygen desaturation index (ODI); total sleep time with SpO2 < 80% (TST < 80), and the lowest SpO2 observed during sleep (SpO2 low). Our findings indicate that increasing oximeter averaging window length progressively underestimates the frequency and magnitude of sleep disordered breathing events at high altitude, as indirectly assessed via the desaturation indexes.
关键词： high altitude,sleep,moving averages,pulse oximetry
更新于2025-09-23 15:21:21
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[IEEE 2019 IEEE 19th International Conference on Nanotechnology (IEEE-NANO) - Macao (2019.7.22-2019.7.26)] 2019 IEEE 19th International Conference on Nanotechnology (IEEE-NANO) - Fiber-optic laser-ultrasound transducer using carbon nanoparticles for intravascular sonothrombolysis
摘要： This paper relates to a genuine wrist pulse oximeter, which is a noninvasive medical device that can measure the pulse rate and oxygen saturation level in a person’s blood. The device is novel due to its innovative design. It is a new type of re?ective oximeter, which has a concave structure for housing the optical source and sensor. The neo-re?ective sensor module of the device is designed to send the sensor data to a nearby intelligent mobile phone using wireless data transmission. The pulse oximeter has been developed and calibrated, and the calibration curve was analyzed. The innovative design of this pulse oximeter would enable the user to wear the low-cost device on one wrist continuously throughout the day, without the inconvenience of a conventional ?nger pulse oximeter.
关键词： wrist oximeter,Biomedical sensor,blood oxygen saturation,re?ective oximetry,pulse oximetry
更新于2025-09-23 15:21:01
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[IEEE 2019 Compound Semiconductor Week (CSW) - Nara, Japan (2019.5.19-2019.5.23)] 2019 Compound Semiconductor Week (CSW) - Quantum entangled photon emitting diodes based on GaAs quantum dots on (111)A: Robustness against increasing temperature
摘要： This paper relates to a genuine wrist pulse oximeter, which is a noninvasive medical device that can measure the pulse rate and oxygen saturation level in a person’s blood. The device is novel due to its innovative design. It is a new type of re?ective oximeter, which has a concave structure for housing the optical source and sensor. The neo-re?ective sensor module of the device is designed to send the sensor data to a nearby intelligent mobile phone using wireless data transmission. The pulse oximeter has been developed and calibrated, and the calibration curve was analyzed. The innovative design of this pulse oximeter would enable the user to wear the low-cost device on one wrist continuously throughout the day, without the inconvenience of a conventional ?nger pulse oximeter.
关键词： blood oxygen saturation,re?ective oximetry,wrist oximeter,Biomedical sensor,pulse oximetry
更新于2025-09-23 15:21:01
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Higha??Accuracy Photoplethysmography Array Using Neara??Infrared Organic Photodiodes with Ultralow Dark Current
摘要： Reflectance oximeters based on organic photodiode (OPD) arrays offer the potential to map blood pulsation and oxygenation via photoplethysmography (PPG) over a large area and beyond the traditional sensing locations. Here, an organic reflectance PPG array based on 16 × 16 OPD pixels is developed. The individual pixels exhibit near-infrared sensitivity up to ≈950 nm and low dark current density in the order of 10?6 mA cm?2. This results in high-quality PPG signals. Analysis of the full PPG waveform yields insight on the artery stiffness and the quality of blood circulation, demonstrating the potential of these arrays beyond pulse oximetry and heart-rate calculation.
关键词： photoplethysmography,organic photodiodes,bulk heterojunction,heartbeat,pulse oximetry
更新于2025-09-23 15:19:57
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Newborn Screening for Critical Congenital Heart Defects Using Pulse Oximetry
摘要： Critical congenital heart defects can lead to serious morbidity and mortality if not found at the appropriate time. Although prenatal ultrasound and postnatal neonatal physical examination can detect the majority of severe congenital heart disease, more than 20% of newborns are still not diagnosed before discharge from the birth hospital. The diagnosis of critical congenital heart defects using pulse oximetry can reduce these diagnostic problems, and it is necessary to consider introducing it as a neonatal screening test in Korea. However, as the prevalence rate of disease and the medical system vary from country to country, it is necessary to study whether this screening test is effective or cost effective in our country. Newborns with a positive result that did not pass a critical congenital heart defects screening using pulse oximetry would require thorough follow-up testing to identify not only severe congenital heart disease but also other potential causes of hypoxia. However, even if the neonate has passed the critical congenital heart defects screening test using pulse oximetry, this screening test has a low sensitivity and a high false positive rate, so it cannot be a perfect screening test for critical congenital heart defects. Therefore, when this screening test is performed at each hospital, it is important to educate and follow the caregivers of signs and symptoms of other congenital heart diseases other than hypoxemia.
关键词： Pulse oximetry,Congenital heart disease,Neonatal screening
更新于2025-09-19 17:15:36
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[IEEE 2019 IEEE 46th Photovoltaic Specialists Conference (PVSC) - Chicago, IL, USA (2019.6.16-2019.6.21)] 2019 IEEE 46th Photovoltaic Specialists Conference (PVSC) - Elevating Low-Quality Silicon Wafers For High-Efficiency Silicon Heterojunction Solar Cell Applications
摘要： This paper relates to a genuine wrist pulse oximeter, which is a noninvasive medical device that can measure the pulse rate and oxygen saturation level in a person’s blood. The device is novel due to its innovative design. It is a new type of re?ective oximeter, which has a concave structure for housing the optical source and sensor. The neo-re?ective sensor module of the device is designed to send the sensor data to a nearby intelligent mobile phone using wireless data transmission. The pulse oximeter has been developed and calibrated, and the calibration curve was analyzed. The innovative design of this pulse oximeter would enable the user to wear the low-cost device on one wrist continuously throughout the day, without the inconvenience of a conventional ?nger pulse oximeter.
关键词： wrist oximeter,Biomedical sensor,blood oxygen saturation,re?ective oximetry,pulse oximetry
更新于2025-09-19 17:13:59
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Organic Multi-Channel Optoelectronic Sensors for Wearable Health Monitoring
摘要： Recent progress in printed optoelectronics and their integration in wearable sensors have created new avenues for research in reflectance photoplethysmography (PPG) and oximetry. The reflection-mode sensor, which consists of light emitters and detectors, is a vital component of reflectance oximeters. Here, we report a systematic study of the reflectance oximeter sensor design in terms of component geometry, light emitter and detector spacing, and the use of an optical barrier between the emitter and the detector to maximize sensor performance. Printed red and near-infrared (NIR) organic light-emitting diodes (OLEDs) and organic photodiodes (OPDs) are used to design three sensor geometries: (1) Rectangular geometry, where square OLEDs are placed at each side of the OPD; (2) Bracket geometry, where the OLEDs are shaped as brackets and placed around the square OPD; (3) Circular geometry, where the OLEDs are shaped as block arcs and placed around the circular OPD. Utilizing the bracket geometry, we observe 39.7% and 18.2% improvement in PPG signal magnitude in the red and NIR channels compared to the rectangular geometry, respectively. Using the circular geometry, we observe 48.6% and 9.2% improvements in the red and NIR channels compared to the rectangular geometry. Furthermore, a wearable two-channel PPG sensor is utilized to add redundancy to the measurement. Finally, inverse-variance weighting and template matching algorithms are implemented to improve the detection of heart rate from the multi-channel PPG signals.
关键词： flexible electronics,printed electronics,pulse oximetry,organic optoelectronics,Reflection photoplethysmography sensor,wearable sensors
更新于2025-09-11 14:15:04
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Pulse Oximetry Screening for Detection of Critical Congenital Heart Defects: Why to Bother?
摘要： Congenital heart defects (CHD) are the commonest form of congenital malformations affecting 6-8 infants per 1,000 live births. Although congenital heart disease remains an important cause of death in infancy, not all forms of major congenital heart disease will be evident at birth or in the early neonatal period. The current screening tools for detection of CHD are: fetal anomaly screening ultrasound and routine examination of newborn prior to discharge from the hospital. Both of these screening tools have a low detection rate and the studies report that up a third of infants with moderate to severe CHD may be discharged home undiagnosed. Critical congenital heart defects (CCHD) are the most serious form of CHD and defined as conditions requiring surgery or intervention within the first 28 days after birth or result in death. The incidence of CCHD is 2-3 per 1,000 live births. Infants with a CCHD are at risk of sudden deterioration following closure of the ductus arteriosus and can result in cardiovascular collapse, acidosis and death. Early diagnosis of such babies would improve survival, as well as reducing the morbidity associated with circulatory collapse prior to recognition of a problem and administration of appropriate treatment. The infants with CCHD remain well while in-utero because of the fetal circulation. However, majority of infants with CCHD are likely to have some degree of hypoxaemia soon after birth. The infants with moderate or severe hypoxia can be detected clinically, but hypoxia in infants with CCHD is often mild soon after birth making it difficult to detect clinically. Interestingly this can be detected by a very simple test – pulse oximetry. Pulse oximetry is a well-established, simple, visible, fast, accurate and non-invasive method of detecting hypoxaemia. This can objectively quantify the degree of hypoxaemia in asymptomatic infants. Pulse oximetry screening has been well-studied in over 230,000 infants enrolled in many well designed research studies and randomised controlled trials. In 2012, a systematic review and meta-analysis published reported that pulse oximetry screening has a high specificity, moderate sensitivity and a low false-positive rate. This meta-analysis identified 13 studies, of over quarter of a million babies, investigating the use of pulse oximetry screening in detection of CCHDs. The overall sensitivity for pulse oximetry screening was 76.5%, the specificity 99.9% and false positive rate 0.14%. This review concluded that pulse oximetry meets criteria for universal screening for detection of CCHDs6. The addition of pulse oximetry screening to exiting screening tools may increase detection rates for CCHD to over 90%. Other studies have established its cost-effectiveness, acceptability to parents and staff and feasibility of implementing screening outside the research context. In addition, the detection of non-critical CHDs and significant non-cardiac conditions such as respiratory problems or early-onset sepsis is reported as an additional benefit of pulse oximetry screening if performed early. These clinically important conditions contributed to up to two third of the reported false positive groups which reduces the clinically non-significant false positivity to half. In 2011, the United States Health and Human Services recommended adding pulse oximetry screening to the uniform newborn panel and since then pulse oximetry screening is being established as a national US government policy. In recent years, pulse oximetry screening has been recommended by several European countries including Switzerland, Ireland and Poland. The UK national Screening Committee (UK NSC) has recently completed a pilot study on feasibility and implications of pulse oximetry screening. However, it is noteworthy to understand that not all CCHDs are likely to be detected on pulse oximetry screening. In summary, pulse oximetry screening is feasible, cost-effective, and acceptable to staff and parents. It qualifies the criteria for universal screening programme for detection of CCHD, and recently has been recommended by many countries to include in their national screening programme. Adding pulse oximetry screening as an adjunct to the existing screening tools can help in detecting up to 90% CCHDs. However, parents and health care professionals need to aware that not infants with CCHD can be detected with pulse oximetry screening and this test has its own limitations.
关键词： Screening,Critical congenital heart defects,Hypoxaemia,Pulse oximetry,CCHD
更新于2025-09-10 09:29:36