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Use of high-power diode laser at 1060?nm for the treatment of vascular lesions
摘要： The use of 1060-nm wavelength light emitted from a high-power diode laser is a novel method for the removal of vascular lesions. Two Caucasian women with Fitzpatrick skin phototype II, who had various vascular lesions, were treated with a 1060-nm high-power diode laser, applying a fluence of 120 J/cm2 and a single pulse duration of 74 milliseconds. Immediate results were that the cherry angiomas became dark and a scab was formed (that remitted 2 weeks after treatment); the telangiectasias and venulectasias disappeared immediately. This technology has reported effective and safe results for removing different types of vascular lesions in the two patients treated. Side effects were those expected for this technique.
关键词： High-power diode laser,Nd: YAG,Venulectasias,Vascular lesions,Cherry angiomas,Telangiectasias
更新于2025-09-16 10:30:52
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[IEEE 2019 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) - Munich, Germany (2019.6.23-2019.6.27)] 2019 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) - Clinical Study for Assessing the Use of a Compact Vecsel-Based Yellow (590 Nm) Laser System in the Treatment of Vascular Lesions
摘要： The treatment of superficial vascular lesions on skin are among the most common sought-after dermatological laser procedures. The treatment method is based on the absorption of laser light by haemoglobin in blood, which results in the transfer of heat and wanted vessel wall damage. The yellow wavelength range is considered ideal for this purpose, because of the high absorption peak of haemoglobin around 577 nm. However, the yellow spectral range is challenging for any laser technology to produce, which is why there are only a few options on the market, notably the pulsed dye laser (PDL), resulting in limited and expensive treatments. We report on a clinical study that assessed the efficacy of a compact high-power yellow laser system designed for the treatment of cutaneous vascular lesions, such as telangiectasia. The laser system is based on frequency-doubled vertical-external-cavity surface-emitting lasers (VECSELs); a novel technology, which has emerged as an attractive alternative to solid-state, and dye lasers due to the enhanced functionality and broad wavelength coverage [1,2]. The system includes a handheld scanner for an easy and fast delivery of laser light onto skin and is capable of emitting 8 W (continuous wave) at the challenging 590 nm wavelength range (see Fig. 1 Left). The first head-to-head clinical study (ClinicalTrials.gov Identifier: NCT03472859) compared the efficacy of the VECSEL-based yellow laser system and a traditional green KTP laser in the treatment of facial telangiectasia [3]. Altogether 24 subjects participated and completed the clinical study. The subjects were randomized to receive KTP treatment on one side of the face and yellow laser treatment on the other side. Each subject received 1–2 treatments with both lasers. The efficacy of the treatments was assessed by blinded investigators using before and after images taken with a Visia imaging system (see Fig. 1 Right). There was no statistically significant difference between the efficacies of the two lasers; 83% of the subjects had at least 50% improvement after the first treatment with the yellow laser system and similar results were observed for the KTP laser. Treatments with the yellow laser system were 4.7-fold faster than with the KTP but subjects experienced more pain, which limited the use of higher fluences. The yellow laser system settings were 5.6-8.1 J/cm2, whereas as green KTP settings were 20–30 J/cm2. In the next study, we will add a cooling device to the yellow laser to enable the use higher fluences, which is expected to lead to better results, as demonstrated by Kapiciogly et al [4].
关键词： vascular lesions,yellow laser,KTP laser,telangiectasia,VECSEL
更新于2025-09-12 10:27:22
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The evaluation of long‐pulsed Nd:YAG laser efficacy and side effects in the treatment of cutaneous vessels on the face and legs
摘要： Background: Long‐pulsed Nd:YAG lasers have been used for the treatment of cutaneous vascular lesions on face and leg veins. Objective: To report our experience with long‐pulsed Nd:YAG lasers for the treatment cutaneous vessels on the face and legs. Materials and Methods: A total of 145 patients with cutaneous vessels on the face and the legs were included in this study. All patients received two treatment sessions, first at the beginning and second after four weeks. Patients were evaluated three times: first at the beginning of the therapy, and second and third after the four weekly follow‐ups. The laser settings of each treatment session were recorded. The physician's assessment of treatment efficiency was taken by comparing gross photograph and clinical evaluation. The grade of improvement, as the percent of reduction in the severity of veins after laser treatment, was determined as follows: <25% improvement (mild); 25%–50% improvement (moderate); 51%–75% improvement (good); and >75% improvement (excellent). The side effects were also recorded. Results: Of the 145 patients who completed the study, 63.6% of patients had vessels on the face, and 36.4% had them on the legs. After the first session, 82.8% of patients have good improvement (51%–75%). After the second session, 78.6% of patients have excellent improvement (>75%). The clinical improvement after the second treatment session was significantly higher than the first treatment session (P ? .05). There were no statistical differences between the treatment areas (P ? .05). The most common side effect was erythema in 12.4% (P ? .05). Conclusion: The Nd:YAG laser is an effective and safe treatment option for the treatment of cutaneous vessels on the face and the legs.
关键词： cutaneous vessels,legs,vascular lesions,long‐pulsed Nd:YAG laser,face
更新于2025-09-12 10:27:22