- 标题
- 摘要
- 关键词
- 实验方案
- 产品
-
Modeling of cancer photothermal therapy using near‐infrared radiation and functionalized graphene nanosheets
摘要： Photothermal therapy using near-infrared radiation and local heating agents can induce selective tumor ablation with limited harm to the surrounding normal tissue. Graphene sheets are promising local heating agents due to their strong absorbance of near-infrared radiation. Experimental studies have been conducted to study the heating effect of graphene in photothermal therapy, yet few efforts have been devoted to the quantitative understanding of energy conversion and transport in such systems. Herein, a computational study of cancer photothermal therapy using near-infrared radiation and graphene is presented using a Monte Carlo approach. A three-dimensional model was built with a cancer cell inside a cube of healthy tissue. Functionalized graphene nanosheets were randomly distributed on the surface of the cancer cell. The effects of the concentration and morphology of the graphene nanosheets on the thermal behavior of the system were quantitatively investigated. The interfacial thermal resistance around the graphene sheets, which affects the transfer of heat in the nanoscale, was also varied to probe its effect on the temperature increase of the cancer cell and the healthy tissue. The results of this study could guide researchers to optimize photothermal therapy with graphene, while the modeling approach has the potential to be applied for investigating alternative treatment plans.
关键词： graphene nanosheet,modeling,cancer photothermal therapy,interfacial thermal resistance,near infrared radiation
更新于2025-09-11 14:15:04
-
[IEEE 2018 19th International Conference on Electronic Packaging Technology (ICEPT) - Shanghai (2018.8.8-2018.8.11)] 2018 19th International Conference on Electronic Packaging Technology (ICEPT) - Facile Preparation of Silver Nanoparticles Decorated Boron Nitride Nanotube Hybrids
摘要： Blending polymer with thermally conductivity Metal nanoparticles-fillers, which can reducing ITR at a high fillers contents, have recently attracted intense attention. The interfacial thermal resistance (ITR) between fillers at a high filler doping contents causes a limited improvement of thermal conductivity. Fortunately, silver nanoparticles decorated fillers have potential to improve thermally conductivity by reducing ITR between fillers at a high filler content. However, how to fabricate pony-size silver nanoparticles decorated fillers hybrids simply is still a challenge. Herein, we report a facile synthesis of decorating boron nitride nanotube (BNNT) hybrids with AgNP (10-20 nm) by replacing between the Ag+ and -OH on the defect sites of BNNT. This strategy is a viable way to prepare metal nanoparticles-fillers which can be used in highly thermal conductivity.
关键词： boron nitride nanotube,thermal conductivity,hybrids,silver nanoparticles,interfacial thermal resistance
更新于2025-09-09 09:28:46