- 标题
- 摘要
- 关键词
- 实验方案
- 产品
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Domain imaging in Fe-doped KNbO3 single crystal via trinocular microscopy and scanning electron microscopy
摘要： Trinocular microscopy with a high spatial resolution is a promising technique for studying the surface morphology of materials. The cleavage face of ferroelectric Fe-doped K niobate (KNbO3) crystals was chemically etched by using HNO3. Trinocular microscopy was used to study the surface morphology of the grown ferroelectric KNbO3 single crystals. The grown surface of the crystal with a 60° domain wall revealed the same interaction and orientations. The results indicate that the type of domain walls that occur in ferroelectric crystals depend on the symmetry of both the nonferroelectric and ferroelectric phases of the crystal.
关键词： Trinocular microscopy,Single crystal,Etching technique,Domain wall
更新于2025-09-23 15:22:29
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Deep learning-based digital in-line holographic microscopy for high resolution with extended field of view
摘要： A digital in-line holographic microscopy (DIHM) with deep learning-based upscaling method is proposed to overcome the trade-off between high resolving power and large field-of-view (FOV). To enhance the spatial resolution of a hologram, a deep neural network was trained with hologram images, which are defocused images with diffraction patterns. The performance of the artificial intelligence-based DIHM method was verified using hologram images obtained by computer simulation and experiments. Upscaled holograms with enhanced image contrast and clear diffraction pattern provided high quality of reconstructed holograms. In addition to the enhancement of reconstructed image at the sample position, details of light scattering pattern could be revealed with the proposed method. The proposed deep learning-based DIHM method is promising for accurate monitoring of many samples and analyzing dynamics of particles or cells in large FOV with detailed 3D information reconstructed from the upscaled holograms.
关键词： 3D measurement,Digital in-line holographic microscopy,Artificial intelligence
更新于2025-09-23 15:22:29
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Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
摘要： Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM.
关键词： Small-fiber neuropathy,Confocal cornea microscopy,Skin biopsy,Amyloid neuropathy,Multiple myeloma
更新于2025-09-23 15:22:29
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Properties of Porous Silicon Precipitated with Nickel for Gas Sensors
摘要： The preparation and properties of modified porous silicon is discussed and a proposal of a sensitive layer for a gas detector is presented. The modification is done by precipitation and electrochemical deposition of nickel. The morphology of sample surfaces is examined by atomic force microscopy and scanning electron microscopy (SEM). SEM-coupled energy dispersive spectroscopy is used to analyse the chemical composition of the samples. Magnetic response is measured with a SQUID magnetometer. Electrochemical impedance spectroscopy is used to study the sensitivity of the samples to isopropanol vapour in the presence of alternating electric current. A series of samples prepared with a higher anodic current density show higher sensitivity to isopropanol vapours in comparison to a lower anodic current.
关键词： Electrochemical Impedance Spectroscopy,Porous Silicon,Gas Sensors,SQUID,Electroless Nickel Deposition,Atomic Force Microscopy
更新于2025-09-23 15:22:29
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[OSA CLEO: Science and Innovations - San Jose, California (2014..-..)] CLEO: 2014 - Terahertz near-field phase contrast imaging
摘要： We demonstrate a method, permitting the observation of dielectric loading of hydrocarbons into a porous coordination polymer nanocrystal (PCP), by spatially resolving the phase difference between the near-field responses of two terahertz resonators.
关键词： Near-field microscopy,terahertz,Spectroscopy,Metamaterials
更新于2025-09-23 15:22:29
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A facile route to diatoms decorated with gold nanoparticles and their optical properties
摘要： This paper presents a facile route for the decoration of biogenic silica from diatoms with gold nanoparticles (AuNPs) with dimensions from 10 to 40 nm. The AuNP decoration on the diatoms is performed through initial attachment of colloidal AuNPs (2 nm) followed by enhancement of the size of the AuNPs by mild reduction of tetrachloroauric (III) acid from solution. The samples were characterised by transmission electron microscopy (TEM), energy-dispersive X-ray analysis, Fourier transform infrared spectroscopy and light spectroscopy in the ultraviolet and visible (UV/Vis) range. The size of the isolated AuNPs on unmodified acid-cleaned diatoms was 10 nm according to TEM micrograph analysis. The measured UV/Vis spectrum showed an absorption peak at 525 nm, which corresponds well to the optical properties of AuNPs of the same size. The extent of decoration with AuNPs of the diatoms was significantly improved after functionalisation with 3-aminopropyltriethoxysilane of the biogenic silica. The absorption peak in the visible range was redshifted to 590 nm due to enlargement of the AuNPs up to 40 nm and clustering of the AuNPs. The AuNP decoration on the hierarchical and complex structured biogenic silica of diatoms might be interesting for biodiagnostic and surface-enhanced Raman spectroscopic applications.
关键词： transmission electron microscopy,optical properties,nanoparticles
更新于2025-09-23 15:22:29
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Phase aberration compensation for digital holographic microscopy based on double fitting and background segmentation
摘要： We propose a purely automatic and accurate phase aberration compensation method in digital holographic microscopy for phase-contrast imaging of living cells. At first, a least-squares fitting procedure is implemented to correct a large proportion of the phase aberrations. Subsequently, the flat phase background is retrieved based on phase gradient and image segmentation. Finally, the residual phase aberrations are eliminated in another least-squares fitting procedure performed within the background region. This method needs no manual intervention or prior knowledge of optical setup. Not only phase curvature but also high order aberrations could be corrected without extra components. It outperforms the phase-variation-minimization method in terms of noise robustness and calculation speed. The performance of the proposed method is demonstrated with simulated and experimental results.
关键词： Phase measurement,Digital holographic microscopy,Aberration compensation
更新于2025-09-23 15:22:29
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A Fluorescence Based-Proliferation Assay for the Identification of Replicating Bacteria Within Host Cells
摘要： Understanding host pathogen interactions is paramount to the development of novel antimicrobials. An important facet of this pursuit is the accurate characterization of pathogen replication within infected host cells. Here we describe the use of a fluorescence-based proliferation assay to identify intracellular populations of replicating bacteria at the subcellular level. Using Staphylococcus aureus as a model Gram-positive bacterial pathogen and macrophages as a model host phagocyte, we demonstrate this assay can be used to reliably identify individual phagocytes that contain replicating bacteria. Furthermore, we demonstrate this assay is compatible with additional cellular probes that enable characterization of cellular compartments in which replicating bacteria reside. Finally, we demonstrate that this assay facilitates the investigation of both Gram-negative and Gram-positive bacteria within host cells.
关键词： microscopy,Staphylococcus,phagolysosome,fluorescence,phagocytosis,macrophage
更新于2025-09-23 15:22:29
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In Vivo Rat Brain Imaging through Full-Field Optical Coherence Microscopy Using an Ultrathin Short Multimode Fiber Probe
摘要： We demonstrate full-field optical coherence microscopy (OCM) using an ultrathin forward-imaging short multimode fiber (SMMF) probe with a core diameter of 50 μm, outer diameter of 125 μm, and length of 7.4 mm, which is a typical graded-index multimode fiber used for optical communications. The axial and lateral resolutions were measured to be 2.14 μm and 2.3 μm, respectively. By inserting the SMMF 4 mm into the cortex of an in vivo rat brain, scanning was performed to a depth of 147 μm from the SMMF facet with a field of view of 47 μm. Three-dimensional (3D) OCM images were obtained at depths ranging from approximately 20 μm to 90 μm. Based on the morphological information of the resliced 3D images and the dependence of the integration of the OCM image signal on the insertion length, the obtained 3D information of nerve fibers has been presented.
关键词： medical optics instrumentation,full-field optical coherence microscopy,endoscopic imaging,fiber optics imaging
更新于2025-09-23 15:22:29
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Quantum Calligraphy: Writing Single-Photon Emitters in a Two-Dimensional Materials Platform
摘要： We present a paradigm for encoding strain into two dimensional materials (2DM) to create and deterministically place single photon emitters (SPEs) in arbitrary locations with nanometer-scale precision. Our material platform consists of a 2DM placed on top of a deformable polymer film. Upon application of sufficient mechanical stress using an atomic force microscope tip, the 2DM/polymer composite deforms, resulting in formation of highly localized strain fields with excellent control and repeatability. We show that SPEs are created and localized at these nanoindents, and exhibit single photon emission up to 60K, the highest temperature reported in these materials. This quantum calligraphy allows deterministic placement and real time design of arbitrary patterns of SPEs for facile coupling with photonic waveguides, cavities and plasmonic structures. In addition to enabling versatile placement of SPEs, these results present a general methodology for imparting strain into 2DM with nanometer-scale precision, providing an invaluable tool for further investigations and future applications of strain engineering of 2DM and 2DM devices.
关键词： tungsten disulfide,atomic force microscopy,two-dimensional materials,single photon emitter,strain engineering
更新于2025-09-23 15:22:29