研究目的
Evaluating the efficacy and safety of a high‐energy 1,064 nm Nd:YAG picosecond‐domain laser for ablation and resurfacing of facial acne scars in Asians.
研究成果
The 1,064 nm picosecond‐domain laser with a high‐energy setting is a safe and effective treatment modality for facial acne scars in Asians. The positive clinical outcomes and the safety profile suggest that the 1,064 nm picosecond‐domain laser is a promising therapeutic option for facial acne scars.
研究不足
Relatively small sample size, efficacy evaluation based on two‐dimensional photography, a follow‐up period of only 3 months, and lack of a comparative group.
1：Experimental Design and Method Selection:
A prospective study design was used to evaluate the efficacy and safety of a 1,064 nm picosecond laser for treating facial acne scars in Asians. The laser treatment was administered every 4 weeks for three sessions.
2：Sample Selection and Data Sources:
Twenty subjects aged 18–50 years with Fitzpatrick skin type III–V and facial acne scars were enrolled.
3：List of Experimental Equipment and Materials:
A picosecond‐domain, 1,064/532 nm Nd:YAG laser (Discovery PICO?; Quanta system S.p.A., Samarate, Italy) was used for all laser treatments.
4：Experimental Procedures and Operational Workflow:
Subjects were treated with a 1,064 nm picosecond laser (8 mm spot,
5：7–0 J/cm2, 5 Hz). Two blinded dermatologists evaluated the pre‐ and 3‐month post‐treatment images. Data Analysis Methods:
Descriptive statistics, Wilcoxon rank‐sum test, Kruskal–Wallis test, and Spearman rank correlation coefficient were used for data analysis.
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