研究目的
To compare the changes in the anterior segment after femtosecond laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) using a dual rotating Scheimpflug (DRS) analyzer.
研究成果
The study found that changes in the posterior corneal surface were greater after FS-LASIK than after SMILE, as indicated by the significant increase in MPE and posterior K in the FS-LASIK group. The degree of CCT thinning after the procedure did not show a significant difference by procedure, although the preoperative LT estimated using the Visumax? program was significantly thicker than the AD estimated using the Mel 90? program. The ACD was significantly decreased after both procedures, but the degree of decrease in the ACD was significantly greater using SMILE than using FS-LASIK.
研究不足
The study was limited by its retrospective design and the specific patient inclusion criteria, which may not represent all patients undergoing FS-LASIK or SMILE. Additionally, the study did not investigate regional posterior corneal shifting, which could provide further insights into the mechanisms of ACD changes.
1:Experimental Design and Method Selection:
A retrospective analysis of 218 eyes (109 patients) that underwent FS-LASIK or SMILE was conducted. The study compared 98 eyes of 49 patients who underwent FS-LASIK to 120 eyes of 60 patients treated with SMILE. A DRS analyzer was used for preoperative and 6-month postoperative anterior segment analyses.
2:Sample Selection and Data Sources:
Patients with myopia up to ?
3:0 diopters (D), astigmatism up to ?0 D, minimum age of 18 years, corrected distance visual acuity (CDVA) of 20/40 or better, and a minimum calculated postoperative residual bed thickness (RBT) of 300 μm were included. List of Experimental Equipment and Materials:
The Galilei? G4 DRS analyzer (software version
4:4) was used for corneal topographic analyses. Experimental Procedures and Operational Workflow:
All measurements were performed between 10 AM and 3 PM with non-dilated pupils under identical lighting conditions. The device was brought into focus and the patient’s eye was aligned along the visual axis by a central fixation light.
5:Data Analysis Methods:
Statistical analyses were performed using SPSS for Windows statistical software (ver. 15.0; SPSS Inc., Chicago, IL, USA). Paired t-tests were used to identify differences between pre- and postoperative values. The independent t-test was used to compare differences between the two groups.
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