研究目的
To compare different parameters of introduced ultrashort pulsed laser processing to enhance the biocompatibility of glass for biomedical use.
研究成果
The HILIRT method effectively enhances the biocompatibility of glass by depositing NFTi coatings. Higher laser power and frequency result in more NFTi fabrication, leading to better cell interaction and adhesion without toxicity. This method offers a non-chemical approach for improving implants for biomedical applications.
研究不足
The study focuses on the effect of laser power and frequency on NFTi fabrication and biocompatibility. Potential areas for optimization include exploring a wider range of laser parameters and other materials for deposition.
1：Experimental Design and Method Selection:
The HILIRT method was used for depositing nanofibrous titanium (NFTi) on glass substrates. The method involves using a picosecond laser beam to ablate materials from a titanium sheet and deposit them on glass substrates.
2：Sample Selection and Data Sources:
Glass microscope slides and Grade 4 titanium substrates were used. The laser system parameters included power ranges from 5 to 12 W and frequencies from 600 to 1200 kHz.
3：List of Experimental Equipment and Materials:
A Ytterbium pulsed fiber laser (IPG Laser Model: YLPP-1-150V30) was used for the HILIRT process. Materials included Titanium CP3–Grade 4 and Plain Glass Microscope Slides by Fisherbrand?.
4：Experimental Procedures and Operational Workflow:
The laser beam was scanned over the microscope slide and titanium substrate to deposit ablated materials on the glass substrate. MarkingMate 1.0 software was used for changing laser parameters.
5：0 software was used for changing laser parameters.
Data Analysis Methods:
5. Data Analysis Methods: SEM, XRD, and Raman spectroscopy were used for structural identification. MTT assay was used to assess biocompatibility.
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