研究目的
Investigating the potential of innovative optical fiber bulk materials using the sol-gel technique for dosimetry in proton therapy.
研究成果
The Gd3+-doped fiber material is a promising candidate for proton therapy dosimetry due to its small size, favorable dose-rate dependency, and weak dependency on proton energy, which reduces the quenching effect in regions of high LET. The Birks constant kB for the Gd3+-doped fiber was found to be significantly lower than for fibers doped with Ce3+ and Cu+, indicating less quenching. This result demonstrates the high potential of this inorganic fiber material for proton therapy dosimetry.
研究不足
The 0.5 mm diameter of the detector may result in the Bragg peak not being fully resolved spatially, and volume averaging may confound the characterization of quenching alone. A detector diameter of 250 μm or less may address the volume averaging issue in the Bragg peak.
1：Experimental Design and Method Selection:
The study investigated the response of a novel silica-based sol-gel glass, doped with Gd3+ ions, to radiation-induced luminescence (RIL) for applications in proton therapy. The methodology included the preparation of doped silica fibers using the sol-gel technique and their testing under proton irradiation.
2：Sample Selection and Data Sources:
The fibers were manufactured at the University of Lille and tested at the TRIUMF Proton Therapy facility with protons of energies ranging from 8.2 to 62.9 MeV and beam currents from 2 to 6 nA.
3：2 to 9 MeV and beam currents from 2 to 6 nA.
List of Experimental Equipment and Materials:
3. List of Experimental Equipment and Materials: The experimental setup included a water phantom, a photomultiplier tube (PMT, Hamamatsu, model H9305-13), and a numerical oscilloscope (Tektronix) for signal recording.
4：Experimental Procedures and Operational Workflow:
The fibers were exposed to proton beams, and their radioluminescence was measured. The dose-rate dependence and quenching effects were analyzed by comparing the fiber signals to those from a Markus chamber.
5：Data Analysis Methods:
The data were analyzed to determine the Birks’ constant, kB, which quantifies the quenching effect. The results were compared with those from fibers doped with Ce3+ and Cu+.
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