研究目的
To develop a highly flexible and selective electrochemical sensor for the detection of dopamine (DA) in human urine, utilizing Pt-Au nanoparticles modified laser-induced graphene (LIG) on a Polydimethylsiloxane (PDMS) substrate.
研究成果
The Pt-AuNPs/LIG/PDMS electrode demonstrated high sensitivity and selectivity for DA detection, even in the presence of interfering substances like UA and AA. Its flexibility and successful application in human urine samples suggest potential for homecare continuous DA monitoring.
研究不足
The sensor's performance under extreme stretching conditions may affect its resistance and sensitivity. The study primarily focused on neutral solutions, and further research is needed to explore its applicability in varying pH conditions.
1：Experimental Design and Method Selection:
The study employed a laser direct writing technique to fabricate LIG on PI film, which was then transferred to a PDMS film. Pt-AuNPs were electroplated onto the LIG/PDMS electrode to enhance electrocatalytic activity.
2：Sample Selection and Data Sources:
Dopamine (DA), uric acid (UA), and ascorbic acid (AA) were used as analytes in PBS and human urine samples.
3：List of Experimental Equipment and Materials:
A CO2 laser for LIG fabrication, electrochemical workstation (CHI 660E), and force gauge (HF-100) for stretchability tests.
4：Experimental Procedures and Operational Workflow:
LIG was fabricated on PI sheets, transferred to PDMS, and modified with Pt-AuNPs via electrodeposition. Electrochemical measurements were conducted to assess sensor performance.
5：Data Analysis Methods:
Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to analyze the electrochemical response of the sensor to DA, UA, and AA.
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