研究目的
Investigating the development of a green, facile method for fabricating highly sensitive and versatile SERS substrates for label-free detection of a wide range of chemical and biological molecules.
研究成果
The study successfully developed a green, facile method for fabricating highly sensitive and versatile SERS substrates. The TNA/Au-based SERS substrate demonstrated outstanding SERS enhancement and provided a versatile platform for chemical and biological sensing. The method also allowed for the synthesis of a bimetallic AuAg SERS substrate, further enhancing detection sensitivity.
研究不足
The study acknowledges challenges related to the high sensitivity and reproducibility of SERS detection, as well as the need for long-term stability and the ability to sense various molecular species.
1:Experimental Design and Method Selection:
The study utilized an invisible ink-inspired process for the fabrication of plasmonic Au-based SERS substrates through an on-site redox strategy using tannic acid (TNA) as a green reagent.
2:Sample Selection and Data Sources:
Various absorbent materials were used, including sponge, printing paper, lens paper, cotton, and cotton swab, treated with TNA solution and HAuCl4 solution to form Au-SERS substrates.
3:List of Experimental Equipment and Materials:
Materials included hydrogen tetrachloroaurate(III) trihydrate, melamine, TNA, methylene blue, and rose bengal sodium salt, among others. Equipment included SEM, TEM, XRD, and UV-VIS spectrophotometry.
4:Experimental Procedures and Operational Workflow:
The process involved soaking substrates in TNA solution, drying, and then reacting with HAuCl4 solution to form Au nanoparticles. SERS measurements were conducted using a micro-Raman spectrometer.
5:Data Analysis Methods:
SERS spectra were analyzed for specific vibrational peaks, and the homogeneity of SERS intensity was assessed through mapping measurements.
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