研究目的
To determine the optimised kV setting for a narrow detector cone-beam CT (CBCT) unit.
研究成果
At a fixed dose per scanning protocol, both low and high kV protocols yield acceptable image quality for a narrow-detector CBCT unit. Higher kV values are preferred as they reduce noise and artefacts, but overall, image quality is similar across kV settings within the same group.
研究不足
The study used phantoms which may not fully represent clinical scenarios; the SEDENTEXCT phantom's homogeneity might not capture subtle clinical differences. Subjectivity in clinical evaluation led to slight inter and intraobserver agreement. Limited mA range prevented full kV range comparison at the same dose, requiring grouping into HD and LD protocols.
1:Experimental Design and Method Selection:
The study used clinical, quantitative, and technical evaluations of image quality with anthropomorphic and polymethyl methacrylate phantoms. Images were acquired using a PaX-i3D Green CBCT device with varying kV settings (75-110 kV) in high-dose and low-dose protocols for large and medium fields of view. Radiation dose was fixed by adjusting mA based on dose-area product. Statistical analysis included bootstrapping and biplot graphs to determine optimal kV.
2:Sample Selection and Data Sources:
An anthropomorphic phantom (SK150, The Phantom Laboratory) and a polymethyl methacrylate phantom (SEDENTEXCT IQ, Leeds Test Objects) were used. Data were collected from CBCT scans under different protocols.
3:List of Experimental Equipment and Materials:
PaX-i3D Green CBCT device (Vatech), anthropomorphic phantom (SK150), polymethyl methacrylate phantom (SEDENTEXCT IQ), ImageJ software for ROI measurements, IBM SPSS Statistics for statistical analysis, elastix for image registration, and a 46'' ED46D LCD display (Samsung) for clinical evaluation.
4:Experimental Procedures and Operational Workflow:
Phantoms were scanned with the CBCT device using specified protocols. Clinical evaluation involved three observers scoring images on various quality parameters. Quantitative evaluation measured grey values and derived metrics. Technical evaluation used automated procedures for segmentation and other parameters. All images were registered and analyzed statistically.
5:Data Analysis Methods:
Weighted kappa for observer agreement, descriptive statistics, principal component analysis with biplots, bootstrapping for statistical comparisons, and normal tests with p≤0.05 significance level.
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PaX-i3D Green CBCT
Not specified
Vatech
Used for acquiring cone-beam CT images with varying kV settings and fields of view for image quality evaluation.
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SK150 Anthropomorphic Phantom
SK150
The Phantom Laboratory
Used for clinical and quantitative evaluations of image quality, containing a natural human skull and soft-tissue simulating material.
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SEDENTEXCT IQ Phantom
SEDENTEXCT IQ
Leeds Test Objects
Used for technical evaluation of image quality, filled with inserts for measurements like segmentation accuracy and CNR.
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ImageJ Software
Not specified
National Institutes of Health
Used for ROI measurements and management in quantitative evaluation.
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IBM SPSS Statistics
Version 22.0
IBM Corp.
Used for statistical analysis, including weighted kappa and other tests.
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elastix
Not specified
Not specified
Used for automatic image registration to ensure matched regions for evaluation.
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ED46D LCD Display
ED46D
Samsung
Used for displaying images during clinical evaluation by observers.
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