研究目的
To avoid decentration of the visual axis of the Boston type 1 keratoprosthesis by performing two concentric trephinations with a femtosecond laser.
研究成果
The femtosecond laser-assisted double trephination technique successfully produced well-centered donor corneas for Boston type 1 keratoprosthesis implantation, with no decentration observed in the 7 cases. This method improves surgical precision and may enhance visual outcomes, suggesting its utility in clinical practice. Future studies should explore long-term effects and broader applications.
研究不足
The study is limited to a small sample size of 7 cases, which may not be generalizable. Potential limitations include the specific laser parameters used and the need for further validation in larger cohorts. Optimization could involve testing different energy settings or applanation techniques.
1：Experimental Design and Method Selection:
The study used a femtosecond laser to perform two concentric trephinations on donor corneas to improve centration of the Boston type 1 keratoprosthesis. The rationale was to minimize centration errors and produce smooth edges without multiple applanation steps.
2：Sample Selection and Data Sources:
A consecutive series of 7 patients (7 eyes) undergoing Boston Kpro implantation from December 2011 to April 2013. Patients provided informed consent and underwent baseline ophthalmic examinations including visual acuity, biomicroscopy, tonometry, ultrasonography, and ultrabiomicroscopy.
3：Patients provided informed consent and underwent baseline ophthalmic examinations including visual acuity, biomicroscopy, tonometry, ultrasonography, and ultrabiomicroscopy.
List of Experimental Equipment and Materials:
3. List of Experimental Equipment and Materials: Equipment included a 150-kHz Intralase? FS laser, artificial anterior chamber (Coronet), optical coherence tomography (OCT) pachymeter integrated in the Schwind Amaris Excimer Laser system, syringes, 3-way connectors, forceps, and sutures. Materials included donor corneas and preservative liquid.
4：Experimental Procedures and Operational Workflow:
The donor cornea was placed in an artificial anterior chamber, pressurized, and applanated under the femtosecond laser. Two consecutive full-thickness cuts were performed: first an 8.5-mm diameter cut at 800 μm depth, then a concentric 3-mm diameter cut at 900 μm depth, using a single applanation ('one-touch' technique). The Kpro was assembled and implanted with sutures, and a bandage lens was applied postoperatively.
5：5-mm diameter cut at 800 μm depth, then a concentric 3-mm diameter cut at 900 μm depth, using a single applanation ('one-touch' technique). The Kpro was assembled and implanted with sutures, and a bandage lens was applied postoperatively.
Data Analysis Methods:
5. Data Analysis Methods: Outcomes measured included visual acuity and postoperative complications, analyzed descriptively over a follow-up period.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容
