研究目的
To report the recent progress on NIR PAI modality and semiconducting contrast agents, outlining the trend in current NIR imaging and providing further direction for the prospective development of PAI systems.
研究成果
The review concludes that NIR PAI has emerged as a promising hybrid imaging modality with integrated properties for both optical and ultrasound imaging techniques. It emphasizes the importance of developing exogenous contrast agents with strong absorption in the NIR region for deep-tissue imaging and the potential of semiconducting polymers and small molecules as versatile platforms for theragnostic applications. The paper also outlines future directions for the development of PAI systems and contrast agents, including the incorporation of lanthanide ions and the use of self-propagation reactions for signal amplification.
研究不足
The review highlights the technical and application constraints of PAI experiments, including the limited penetration depth of optical imaging techniques and the need for exogenous contrast agents for deep-tissue imaging. It also discusses potential areas for optimization, such as the development of biodegradable and stimuli-responsive contrast agents.
