研究目的
Investigating the potential of photoacoustic imaging as a noninvasive technique for monitoring periodontal health, addressing the limitations of the current gold-standard periodontal probe.
研究成果
Photoacoustic imaging provides a noninvasive method for monitoring periodontal health with significantly more spatial information and precision than the gold-standard periodontal probe. This technique presents an opportunity for dental clinicians to move away from manual probing and toward photoacoustic image-guided diagnostics.
研究不足
Due to the size of the PA-US transducer, only anterior teeth could be imaged. The subject had good oral hygiene and did not have deep pockets indicative of periodontal disease. The dynamic nature of the periodontal pocket may have contributed to small variations in measurements across different days.
1:Experimental Design and Method Selection:
Utilized a range of ultrasound frequencies (16-40 MHz) to image the periodontium and a contrast medium based on cuttlefish ink to label the pockets.
2:Sample Selection and Data Sources:
Enrolled a healthy 22-year old adult female with good oral hygiene. Teeth numbers 7-10 and 22-27 were imaged.
3:List of Experimental Equipment and Materials:
Used a laser-integrated high frequency ultrasound system (Vevo LAZR), medical head immobilizer, disposable dental cheek retractors, and contrast agent solutions prepared from cuttlefish ink.
4:Experimental Procedures and Operational Workflow:
Administered contrast agent to the subgingival pockets, performed photoacoustic imaging, and analyzed images to measure pocket depths.
5:Data Analysis Methods:
Images were analyzed using ImageJ to determine the penetration of contrast agent and quantify pocket depths.
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