- 标题
- 摘要
- 关键词
- 实验方案
- 产品
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Multifunctional Thermosensitive Liposomes Based on Natural Phase Change Material: Near-Infrared Light-Triggered Drug Release and Multimodal Imaging Guided Cancer Combination Therapy
摘要： Multifunctional theranostic nanoplatforms (NPs) in response to environment stimulations for on-demand drug release are highly desirable. Herein, the near-infrared (NIR)-absorbing dye, indocyanine green (ICG) and the antitumor drug, doxorubicin (DOX) were efficiently co-encapsulated into the thermosensitive liposomes based on natural phase change material (PCM). Folate and conjugated gadolinium chelate-modified liposome shells enhance active targeting and magnetic resonance (MR) performance of the NPs while maintaining the size of the NPs. The ICG/DOX loaded and gadolinium chelates conjugated temperature-sensitive liposomes nanoplatforms (ID@TSL-Gd NPs) exhibited NIR-triggered drug release and prominent chemo-, photothermal, photodynamic therapy properties. With the co-encapsulated ICG, DOX and the conjugated gadolinium chelates, the ID@TSL-Gd NPs can be used for triple-modal imaging (fluorescence/photoacoustic/magnetic resonance imaging, FL/PAI/MRI) guided combination tumor therapy (chemotherapy, photothermotherapy and photodynamic therapy, Chemo/PTT/PDT). After tail vein injection, the ID@TSL-Gd NPs accumulated effectively in subcutaneous HeLa tumor of mice. The tumor was effectively suppressed by accurate imaging guided NIR triggered phototherapy and chemotherapy, and no tumor regression and side effects were observed. In summary, the prepared ID@TSL-Gd NPs achieved multimodal imaging-guided cancer combination therapy, providing a promising platform for improving diagnosis and treatment of cancer.
关键词： Multimodal imaging,Liposomes,Thermosensitive,Combination therapy,Phase change material
更新于2025-11-21 11:08:12
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[IEEE 2018 4th International Conference on Renewable Energies for Developing Countries (REDEC) - Beirut, Lebanon (2018.11.1-2018.11.2)] 2018 4th International Conference on Renewable Energies for Developing Countries (REDEC) - Phase Change Materials in a Domestic Solar Hot Water Storage Tank of the Lebanese Market
摘要： The availability of some kinds of renewable energy resources is un-continuous, for example the solar collectors can only produce heat when the sun is shining. Thermal Energy Storage (TES) is crucial to match between the intermittent solar heat supply and the heat demand. In this paper, a Phase Change Material (PCM) is integrated in the Domestic Solar Hot Water Storage Tank (DSHWST) as a Latent Heat Storage (LHT). Based on the application requirements in Lebanon, a suitable PCM is selected. While this PCM solidifies, it releases its heat and keeps the water inside the DSHWST warmer than 55 oC along 10 hours. The needed mass of PCM was calculated and two types of containers were investigated: the tubes and the spheres. As well as, the comparison between DSHWST integrated with PCM (DSHWST-PCM) and the Conventional Domestic Solar Hot Water Storage Tank (CDSHWST) is introduced, in order to examine the performance of PCM heating against that with an Electrical Resistance (ER). Features are expressed in terms of system payback and CO2 emission. Due to the issue of electrical power availability in Lebanon, the PCM integrated in The DSHWST has the following two advantages: yearly, reducing the primary electricity power by about 6.5 MWh and get rid of about 5.5 tons of CO2.
关键词： Thermal Energy Storage,Phase Change Material,Hot Water Storage Tank,Lebanon
更新于2025-09-23 15:22:29
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Design of a novel nanoscale high-performance phase-change silicon photonic switch
摘要： We report the design of a novel high static performance on-off photonic switch by embedding the nanoscale phase-change material Ge2Sb2Te5 into a silicon-on-insulator waveguide. The state of the proposed switch can be changed using electrical/optical pulses, and no electrical bias is needed to maintain a particular state. The fundamental mode propagating through the silicon waveguide drastically alters its properties because of the large index change at the Si-Ge2Sb2Te5 interface and absorption in Ge2Sb2Te5. The photonic switch made of the silicon waveguide embedded with Ge2Sb2Te5 of volume 400 nm × 180 nm × 450 nm (length × height × width) provides a high extinction ratio of 43 dB with a low insertion loss of 2.76 dB in ON state at the communication wavelength of 1550 nm. There is a trade-off between the insertion loss and the extinction ratio. For 10 dB extinction ratio, the insertion loss can be as low as 1.2 dB with an extremely low active volume of 400 nm × 30 nm × 450 nm (length × height × width). Further, spectral response investigations reveal that this switch maintains an extinction ratio of more than 30 dB in the wavelength range of 1500–1600 nm. The high static performance of the photonic switch reported here is a direct consequence of the proper dimensions of the active volume of Ge2Sb2Te5 and its incorporation into the silicon-on-insulator waveguide. We also propose figure-of-merit for bias-free (nonvolatile) photonic switches that considers relevant parameters of static performance.
关键词： Silicon photonics,Phase-change material,Nanophotonics,Photonic switch
更新于2025-09-23 15:21:21
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A phase-change thin film-tuned photonic crystal device
摘要： This paper reports a tunable photonic device that incorporates a thin layer of phase-change material, Ge2Sb2Te5 (GST), in a photonic crystal (PC) structure. The PC structure is based on a one-dimensional grating waveguide with a metal cladding. The metal-cladded PC structure supports a guided-mode resonance (GMR) that selectively absorbs light at a particular wavelength. Inserting the GST material into the gating waveguide makes it possible to control the GMR mode. Here, the GST-PC device was numerically designed and optimized to obtain significant tuning of the GMR mode around 1550 nm. The tuning phenomena were experimentally demonstrated by the heat-induced phase change between crystalline and amorphous phases of the GST thin film. A spectral shift of the resonant wavelength from 1440 nm to 1610 nm was achieved via the crystallization process. The phase tuning of GST exhibits good repeatability as demonstrated by switching between amorphous and crystalline phases of GST for multiple cycles. The GST-PC device represents a new approach for tuning optical resonances with potential applications including but not limited to integrated photonic circuits, optical communications, and high-performance optical filters.
关键词： tunable filter,Photonic crystal,phase-change material
更新于2025-09-23 15:21:01
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Performance enhancement of copper indium diselenide photovoltaic module using inorganic phase change material
摘要： The work presents the method to increase the electrical efficiency and power output of photovoltaic (PV) panel with the use of phase change material (PCM). CaCl2.6H2O–Fe3Cl2.6H2O eutectic has a suitable melting point and high latent heat for temperature regulation of PV panel. The work has been focused on the experimental setup and simulation heat extraction from the PV panel with the use of ANSYS software. A modification of copper indium diselenide (CIS) PV module from Solar Frontier (SF170-S) was made with a eutectic mixture (70:30) of calcium chloride hexahydrate (70%) and iron (III) chloride hexahydrate phase change material. The cell temperature of the PV panel with and without PCM was measured and compared for two typical days. The simulation of the PV-PCM systems comprising both PV panels was performed using ANSYS (fluent) software, followed by the comparison of the results actual experimental data. The experimental results show that the maximum temperature difference on the surface of PV panel without PCM was 9°C higher than that on the panel with PCM in a period of 1 day. Referring to experimental results, the calculation of the maximum and average increase of power gain was made for PV-PCM panel. Final results show that the electricity production of PV-PCM panel was higher for 96.55 Whr in a particular day of experimentation.
关键词： phase change material,ANSYS,electrical efficiency,power gain,photovoltaic module
更新于2025-09-23 15:21:01
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Exergy and energy analysis of wavy tubes photovoltaic-thermal systems using microencapsulated PCM nano-slurry coolant fluid
摘要： To develop a more efficient water-cooled photovoltaic-thermal system, energy and exergy analysis of a photovoltaic-thermal system with wavy tubes are investigated numerically using different coolant fluids. A comparison between the straight tube and wavy tubes is conducted for various wavelengths and wave amplitudes. The geometrical parameters of the wavy tubes as well as the velocity of the coolant fluid are examined. Besides, the consequences of coolant fluid including water, Ag/water nanofluid, microencapsulated phase change material slurry, and also a new type of cooling fluid called microencapsulated phase change material nano-slurry are studied. The results show that the electrical, thermal, and exergy efficiencies of the photovoltaic-thermal module enhance by using the wavy tubes compared with the corresponding straight tubes. By declining wavelength in a constant wavelength/amplitude, the heat absorbed by the heat transfer fluid raises. For the best configuration, the primary and exergy efficiencies of the module increase by 6.06% and 4.25%, respectively, for the wavy tubes system compared with those for the straight unit. Furthermore, in both configurations, by increasing the inlet velocity, the overall performance of the photovoltaic-thermal module increases due to a higher heat transfer rate. The results also reveal that among different types of cooling fluids, the microencapsulated phase change material nano-slurry has higher performance in terms of both energy and exergy efficiencies due to having higher thermal conductivity and heat capacity. By employing the wavy tube and the novel proposed coolant fluid, the primary and exergy efficiencies increase in comparison with a typical photovoltaic-thermal module.
关键词： Energy,Microencapsulated phase change material slurry,Wavy tube,Nanofluid,Photovoltaic-thermal module,Exergy
更新于2025-09-23 15:21:01
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Experimental analysis of a photovoltaic/thermoelectric generator using cobalt oxide nanofluid and phase change material heat sink
摘要： Nowadays, photovoltaic panels have been known as effective devices to harness solar energy. These panels mainly convert the UV and visible areas of the solar spectrum into electricity and the rest of the energy is dissipated. One of the favorable methods to take advantage of such dissipated heat is to combine thermoelectric generators (TEG) utilizing the IR area of the solar radiation with photovoltaic panels. Having the different and opposite impact on the efficiency of thermal photovoltaic cells (PV/T) and thermoelectric generators (TEG), the system operating temperature appears as a critical parameter in the productivity of a PV/T-TEG hybrid unit. In the present study, a novel heat sink for a PV/T-TEG hybrid system is introduced. The effectiveness of simultaneous usage of the Co3O4/water nanofluid and the improved phase change material (paraffin wax/Alumina powder) as a cooling method on the performance of the PV/T-TEG is examined throughout an experimental study. Then, the overall electrical, thermal and exergy efficiency of such a system is compared to the units with divers working fluids including water and 0.25%, 0.5%, and 1% nanofluid and the unit consisting of 1% nanofluid with non-enhanced PCM cooling method. The results reveal that using 1% nanofluid with enhanced PCM, as a cooling method, would improve the overall electrical efficiency by 12.28% compared to water cooling technique. Also, an increase of 11.6% in the exergy efficiency of the PV/T-TEG is observed in comparison with PV/T-TEG with the water cooling method. Hence, it could be concluded that the combination of this unit could contribute to harnessing solar energy more efficiently, compared to solo photovoltaic panels.
关键词： Photovoltaic thermal,Solar energy,Nanofluid,Thermoelectric generator,Phase change material
更新于2025-09-23 15:21:01
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Experimental study for the application of different cooling techniques in photovoltaic (PV) panels
摘要： This article contains the experimental investigations of different cooling methods used for photovoltaic (PV) panels. Phase change material (PCM), thermoelectric (TE) and aluminum fins were chosen as the cooling methods. The CaCl2·6H2O is chosen as one of the PCM which is widely used in the cooling of PVs and the other is the PCM with melting temperature above the surface temperature of the PV panel. By using TE material in different numbers (6, 8 and 12) and aluminum fins in different layouts, surface temperatures and output powers of PV panels were compared. It is observed that the PCM which is not chosen appropriately has insulation feature in the PV panel and enhances the temperature of the panel and decreases the output power. When the most successful cooling methods were tested under the same environmental conditions, PV with fin system produced the highest power generation of 47.88 W while PV with PCM and TEM produced the lowest power generation of 44.26 W.
关键词： Thermoelectric module,Photovoltaic,Fin,Cooling,Phase change material
更新于2025-09-23 15:21:01
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Unidirectional photonic circuit with a phase-change Fano resonator
摘要： We demonstrate that the integration of a phase-change material (PCM) in one of the two microresonators of a photonic circuit, coupled to a bus waveguide, can lead to unidirectional Fano resonances and to the emergence of a unidirectional transmission window. The phase change is caused by light-induced heating and is accompanied by an abrupt increase in the extinction coefficient of the PCM resonator. Due to the photonic circuit asymmetry, the critical value of the input light intensity triggering the phase change is strongly dependent on the input light direction. The latter determines the unidirectional nature of the emerging transmission window. This effect can be utilized in on-chip magnetic-free isolators and Q switches.
关键词： optical isolators,phase-change material,photonic circuit,unidirectional transmission,Fano resonances
更新于2025-09-23 15:21:01
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Dynamically tunable perfect absorption based on the phase transition of vanadium dioxide with aluminum hole arrays
摘要： Integrating plasmonic nanostructures with functional materials can further control over the optical resonant responses. A perfect absorber (PA) consisting of aluminum (Al) ring array intercalated with vanadium dioxide (VO2) disk is presented. The resonance wavelength of absorption peak can be tuned over a wide range in the visible (Vis) and near-infrared (NIR) regimes. The absorption peak shifts from 770 nm to 1336 nm while VO2 undergoes a structural transition from metallic phase (m-VO2) to insulator phase (i-VO2), resulting in a relative 73.5% wavelength shift. In addition, the absorption peak is strongly dependent on the height and radius of the ring disk as well as the period of lattice. Our work also suggests that the designed VO2-based absorber has the potential to overcome the di?culty in performing dynamically tunable resonances and near-unity absorbance with wide angle of incidence as well as weak polarization dependence.
关键词： Vanadium dioxide (VO2),Visible and near-infrared spectral,Phase change material,Perfect absorption
更新于2025-09-23 15:21:01